The SYMIX™ enables separate storage, reconstitution, and direct injection in the same device. Prior to administration, the components are mixed in the device, eliminating the need for multiple separate components (such as vials, adapters, and extra syringes) and complex transfer steps.
The SYMIX™ Dual-Chamber syringe uses an internal bypass to enable mixing of the two components within the barrel. As the user pushes the plunger, the rear stopper advances to the bypass zone, allowing the rear component (mainly liquid) to flow through the bypass channel into the front chamber to meet the second component. After mixing, the plunger continues its stroke like a standard syringe, delivering the full dose directly from the same container. By consolidating these elements, SYMIX™ simplifies preparation, significantly reduces handling steps, and helps minimize contamination risk.
SYMIX™ combines drug storage, reconstitution, and injection in one device, simplifying the entire process.
Ease of Use & Handling The integrated dual-chamber design reduces device assembly and preparation complexity, enabling a more intuitive injection workflow.
Accurate Dose Preparation Pre-measured drug and diluent are combined within a single system, helping ensure consistent preparation while minimizing handling errors.
Reducing Contamination Risk The closed system minimizes exposure to external contaminants and particulate matter.
Stable Storage Provides separate storage of stability-sensitive injectable drug products, preserving chemical and physical stability, maintaining potency, and supporting shelf life until the point of administration.
Customizable Platform SYMIX™ can be engineered in a glass or polymer barrel, with custom chamber volumes and mixing mechanisms tailored to your drug’s requirements and required usability.
Flexible Needle Interface/ Compatibility Flexible interfaces support common needle types such as Luer-lock and pen needles, configurable per project. SYMIX™ can also integrate with a variety of safety-needle options, including DALIMED’s SAN® safety needle family.
| Description | Details |
| Barrel material | Glass (Type I borosilicate) |
| Dual chamber configurations | Lyophilized + diluent; liquid + liquid; powder + liquid |
| Delivered volume | Low-volume: 1.5 / 2.4 mL High-volume: 3.3 / 4.3 mL |
| Needle compatibility | Luer lock |
| Sterility needle | Pre-sterilized on request (project-specific methods).Luer-lock hypodermic needle |
| Customization options | Volumes, usability, ergonomics, needle types including safety needles, branding – logo, colors, and labeling. |
Tailored to your therapy, formulation, and device requirements. Our team will customize your product to ensure complete compatibility, functionality, and usability.
| Category | Customizable Options |
| Barrel material | Polymer (COC/COP). Selected per drug compatibility and stability requirements. |
| Container format | Dual-chamber barrel with integrated internal bypasses; chamber sizes and ratios tailored to specific formulation needs. |
| Delivered volume | Custom volumes and chamber ratios available per project. |
| Usability mode | Push-to-mix, twist-to-mix, or hybrid push-rotate |
| Needle interface | Multiple standard and custom options, configurable per project (e.g., pen-injector needle) |
| Safety needle | DALIMED’s SAN® family passive safety needles (Luer-lock compatible) or manual safety needles per project needs. |
| Ergonomics | Plunger rod, finger flange & thumb pad shapes and grip |
| Container closure integrity | Optional additional CCI cap to support container‑closure integrity requirements. |
| Branding & packaging | Colors, textures, scale markings, mix/inject indicators. |
| Supply | can be supplied as sub‑assemblies and/or individual components, per your specific production processes. The sub-assemblies and/or components can be packed in bulk or in trays for your production line, with sterile or non-sterile supply options depending on your needs. |
| Special configuration | Injection liquid after liquid |
DALIMED offers customized configurations of the SYMIXTM for the drug Aripiprazole and for the drug Leuprolide.
* This product is under development
DALIMED has been developing drug delivery devices from concept to commercialization since 2003, serving pharmaceutical and medical device companies.
Our injectable solutions are designed to improve patient compliance with biologic, biosimilar, and generic therapies, offering greater ease, comfort, and enabling simple self-administration. With expertise across the full product lifecycle, we provide both market-ready devices and customizable solutions tailored to specific needs-covering everything from design and development to verification, validation, and compliance with all relevant standards and regulations.
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